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Immunoflourescence: localization of LANA and SP1 in

Immunoflourescence: localization of LANA and SP1 in
KSHV infected cells (BC-3)

Projects

Mechanisms of Oncogenesis by Gammaherpesvirus

Mechanisms Involved in the Maintenance of KSHV Episomes During Host Cell Division

EBNA3C Targeting of the Alpha Integrin Promoter :The Potential Molecular Link Between EBV and Metastisis

EBNA3C's role in deregulation of the cell cycle

Mechanism of Inhibition of Viral Lytic Replication by Kaposi’s Sarcoma Associated Herpesvirus Encoded Latency Associated Nuclear Antigen

Inhibiton of the Anti-metastatic Effects of Nm23: A Potential Molecular Link Between EBV and Metastisis

Construction of a KSHV-GFP Recombinant Virus and the Development of a System to Assess Gene functions of KSHV

Schematic representation of a proposed mechanism of persistence of KSHV DNA in DSHV infected body cavity-based lymphoma cell
Immuno-FISH showing colocalization of LANA and KSHV DNA (Z6) on chromosome spread of KSHV infected BC-3 cells
Localization of KSHVDNA(Z8) and LANA on chromosome
spread of KSHV infected BC3 cells

Modulation of Cox-2 expression (an indicator of metastasis) by Nm23H1(a known suppressor of Metastasis)

Kaposi Sarcoma Associated Herpesvirus:- Elucidation of the Mechanism of the Latent DNA Replication

Development of an in vivo animal model for evaluation of the role of Nm23H1 and EBNA proteins on the ability of cell lines to metastasize in mice. Link Between EBV and Metastasis

Additional Projects

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